南京大学学报(自然科学版) ›› 2012, Vol. 48 ›› Issue (5): 559–564.
Wang Xiao-Feng，Zhang Dong，Tu-Juan**
王萧峰，章东，屠娟
摘要： Destruction of ultrasound contrast agents(UCAs) and the associated emissions arc very important in some diagnostic and therapeutic applications.The UCA’s acoustic response，especially their inertial cavitation(lC)thresholds, depends on gas content and shell properties of the UCA. In the
present work, transient acoustic emissions induced by lC activities are characterized by broadband noise in the destruction process, which is used as an indicator to determine the lC threshold for UCAs. Experiments were performed to measure the lC thresholds for two kinds of UCAs(Optison and
SonoVue) as a function of the UCAs’concentration and acoustical pulse length.The results show that albumin-shelled UCAs (Optison) might have higher lC threshold than lipid-shelled ones (SonoVue).
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