腺苷酸激酶催化产物释放过程中的水化动力学研究

孔剑阳,李文飞,王炜

Hydration process in the product releasing of the enzymatic cycle of Adenylate Kinase

Jianyang Kong,Wenfei Li,Wei Wang

图2 (a) DD，TD态下AdK在构象闭态和构象开态中Mg²⁺配位水分子数目（误差棒表示对应状态的水分子数目的标准误差）；

Fig.2 (a) Average number of $H_{2} O$ coordinating with Mg²⁺ in DD and TD states at the closed and open states （error bar indicates the standard error of the number of $H_{2} O$ in the corresponding state）, (b) representative structures showing the coordination between Mg²⁺ and $H_{2} O$ in DD and TD states at the closed and open state (b) Mg²⁺配位结构示意图，左上、右上、左下、右下依次为DD态的构象闭态、DD态的构象开态、TD态的构象闭态以及TD态的构象开态，Mg²⁺由绛红色小球表示