Abstract: A new­type optical microcavity structure with distributed Bragg reflectors(DBRs)was fabricated.The DBRs were grown by conformal deposition method of silicon nitride and silicon oxide multilayers alternatively on patterned substrates.The optical microcavity could both realize the photon confinement and the space limitation of the quantum dots solution.The photoluminescence(PL)behavior of CdSe@ZnS colloidal quantum dots in aqueous solution was studied in the optical microcavities.It could be observed that the PL intensity of the CdSe@ZnS colloidal quantum dots in solution decreased with the concentration increasing in the new­type optical microcavity.However，in the common container，the PL intensity of the CdSe@ZnS colloidal quantum dots in aqueous solution increased with the concentration increasing.When the diameter of the new­type optical microcavity is small enough，the emission peak wavelength will blue shift with increasing quantum dots concentration.This is different from the shift behavior of the emission peak wavelength in the common container.It can be deduced that，such different phenomena of the PL of the quantum dots in microcavity is due to the cavity confinement effect of the new­type optical microcavities，which deeply influences the PL mechanism of the CdSe@ZnS colloidal quantum dots inside them.